Today’s AM talks in SS told the story of harnessing
biomolecules and proteins to produce electricity. David Baker gave a thorough
introduction to the challenges of wiring PSI to an electrode. He discussed the many issues facing this system including the density of PSI molecules at the
surface and the long intra-molecular distance over which electron transport
must occur. His group has devised a creative 3D architecture that integrates a
built-in osmium redox shuttle to achieve high current density.
The next speaker, Houman Yaghoubi described his method of
wiring up the reaction center in an organized SAM via docking at cytochrome C
SAMs. This approach not only affords control over the placement and the
orientation of RC but also evades some of the conductivity issues that
inherently occur due to the pocket in RC.
Rather than utilizing a native protein, Leslie Dutton has
worked on producing stable “plastic proteins” out of a short, repeating peptide
sequence. These can incorporate biomolecules for functions such as oxygen and
electron transport. They have also demonstrated their ability to tune these
proteins to mimic various other biological functions.
All 3 of these talks demonstrated deep understanding of the
fundamental challenges facing biomimetic charge transport mechanisms. The
mastery required for these research groups to be able to manipulate biology
into non-native functionality is unbelievable! However, the charge transport
pathways in biomolecules at the angstrom level in are still largely unknown. In
order to improve the biomimetic designs, we NEED to be able to model the
systems. Therefore, Anders Blom described his advances towards an organic
electronics software package. His group
has developed a package that uses DFT capable of computing a wide array of
electronic properties of arbitrary organic molecules or macromolecules.
This field is progressing so quickly—we’ll soon be at the
point of utilizing self-assembly to rationally design bio-electrical systems.
Let’s thank our sponsors:
Aldrich Materials Science
Asylum Research, an Oxford Instruments Company
Biolin Scientific
Journal of Materials Science
Journal of the Royal Society Interface
Springer
Well done.
Make sure to come to the poster session tonight from 8-11
tonight!